Benefits of reperfusion beyond infarct size limitation
نویسندگان
چکیده
منابع مشابه
Myocardial Reperfusion, Limitation of Infarct Size, Reduction of Left Ventricular Dysfunction, and Improved Survival
For nearly a decade, it has been appreciated that 1) thrombotic occlusion of an epicardial coronary artery is usually the proximate cause of acute myocardial infarction; 2) after sudden and sustained total occlusion of such a vessel, the course of myocardial necrosis is generally rapid and relentless (in most cases, the process is completed within 3 or 4 hours of the coronary occlusion, in 6 ho...
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Introduction: In the current study, protective effect of natural honey applied during ischemia/reperfusion (I/R) was studied on infarct size in ischemic heartheart. Methods: Ischemic hearthearts (n=8 per group) were mounted on a Langendorff apparatus at constant pressure then subjected to 30 min regional ischemia followed by 120 min reperfusion. In control group, the hearts were perfused by ...
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The possibility of predicting myocardial infarct size from early enzyme measurements was studied using a physiological two compartment distribution model. Based on this the time dependent appearance function in plasma was calculated for creatine kinase, aspartate aminotransferase, and lactate dehydrogenase in 29 patients suffering from acute myocardial infarction. On average, the appearance fun...
متن کاملMyocardial reperfusion, limitation of infarct size, reduction of left ventricular dysfunction, and improved survival. Should the paradigm be expanded?
For nearly a decade, it has been appreciated that 1) thrombotic occlusion of an epicardial coronary artery is usually the proximate cause of acute myocardial infarction; 2) after sudden and sustained total occlusion of such a vessel, the course of myocardial necrosis is generally rapid and relentless (in most cases, the process is completed within 3 or 4 hours of the coronary occlusion, in 6 ho...
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Brener et al. (1) show in a substudy of INFUSE-AMI (Intracoronary Abciximab and Aspiration Thrombectomy in Patients With Large Anterior Myocardial Infarction) trial that myocardial blush grade (MBG) 2/3 in a relatively small study population of 452 patients is associated with smaller infarct size, less microvascular obstruction, improved ejection fraction as assessed by contrast-enhanced cardia...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2009
ISSN: 0008-6363
DOI: 10.1093/cvr/cvp032